From: The AGE-RAGE axis associates with chronic pulmonary diseases and smoking in the Rotterdam study
Parameters | Total population | COPD | No COPD |
---|---|---|---|
N | 2577 | 613 (23.8%) | 1964 (76.2%) |
Age(years)* | 72.28 ± 9.29 | 75.29 ± 8.72 | 71.35 ± 9.26 |
Sex | Â | ||
Male/n(%)* | 1148 (44.5%) | 351 (57.3%) | 797 (40.6%) |
Female/n(%)* | 1429 (55.5%) | 262 (42.7%) | 1167 (59.4%) |
RS cohort | Â | ||
RS I | 615 (23.9%) | 213 (34.7%) | 402 (20.5%) |
RS II | 923 (35.8%) | 246 (40.1%) | 677 (34.5%) |
RS III | 1039 (40.3%) | 154 (25.1%) | 885 (45.1%) |
SAF* | 2.39 ± 0.49 | 2.50 ± 0.52 | 2.36 ± 0.47 |
FEV1%predicted * | 97.89 ± 18.36 | 83.91 ± 18.25 | 102.25 ± 16.08 |
DLCOc # | 7.82 ± 1.71 | 7.64 ± 1.97 | 7.85 ± 1.68 |
DLCOc/VA * | 1.51 ± 0.23 | 1.36 ± 0.25 | 1.53 ± 0.22 |
N for sRAGE & EN-RAGE | 1192 | 83(7.0%) | 1109(93.0%) |
sRAGE+ | 2.97 ± 1.63 | 2.54 ± 1.23 | 3.00 ± 1.66 |
EN-RAGE* | 13.00 ± 8.22 | 15.89 ± 11.59 | 12.79 ± 7.87 |
Asthma | 215 (8.3%) | 34 (5.5%) | 181 (9.2%) |
Smoking Status (N = 2575) |  | ||
Never Smokers* | 848(32.9%) | 106 (17.3%) | 742 (37.8%) |
Ex-Smokers* | 1483 (57.5%) | 409 (66.7%) | 1074 (54.7%) |
Current Smokers* | 244 (9.5%) | 98 (16.0%) | 146 (7.4%) |
T2DM | 389 (15.1%) | 101 (16.5%) | 288 (14.7%) |
Oral corticosteroids+ | 139 | 43 (7.2%) | 96 (5.0%) |
Inhaled corticosteroids* | 196 | 83 (13.8%) | 113 (5.9%) |