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Fig. 6 | Respiratory Research

Fig. 6

From: Fine particulate matter 2.5 induces susceptibility to Pseudomonas aeruginosa infection via expansion of PD-L1high neutrophils in mice

Fig. 6

Blocking of PD-L1 reduces susceptibility to P. aeruginosa induced by PM2.5 exposure. (A) Schematic of the experimental model. (B) Bacterial burden in the BALF (upper left), lung (upper right), liver (lower left), and spleen (lower right) are shown in colony forming units (CFU). (C) Representative histological images of lungs by H&E staining. (D) Inflammation scores estimated from lung tissues with H&E staining. (E) The counts of neutrophils in the BALF. (F) Expression of Tnf (left), Il1b (middle), and Il6 (right) in mouse lungs at mRNA level. The data are shown as means ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001

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Respiratory Research

ISSN: 1465-993X

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