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Fig. 4 | Respiratory Research

Fig. 4

From: Fine particulate matter 2.5 induces susceptibility to Pseudomonas aeruginosa infection via expansion of PD-L1high neutrophils in mice

Fig. 4

PM2.5-exposed mice are susceptible to P. aeruginosa. (A) Schematic of the experimental model. (B) Survival curves of mice. (C-D) Body temperature (C) and weight changes (D) following infection. (E) Bacterial burden in the BALF (upper left), lung (upper right), liver (lower left), and spleen (lower right) are shown in colony forming units (CFU). (F) The counts of neutrophils in the BALF. (H) Representative histological images of lungs by H&E staining. (G) Inflammation scores estimated from lung tissues with H&E staining. (I) Expression of Tnf (left), Il1b (middle), and Il6 (right) in mouse lungs at mRNA level. The data are shown as means ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001

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Respiratory Research

ISSN: 1465-993X

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