Table 1 Characteristics of the study participants with matched RNA-seq data from sputum

Age (years)

32.50 [26.50, 43.25]

24.00 [21.50, 28.50]

29.00 [25.75, 37.00]

0.125

Female/Male

2/6 (25.0/75.0)

2/9 (18.2/81.8)

1/3 (25.0/75.0)

1

White Race

7 (87.5)

11 (100.0)

3 (75.0)

0.15

Never Married

5 (62.5)

8 ( 72.7)

3 (75.0)

1

Body Mass Index

25.47 [22.52, 31.75]

24.71 [23.68, 34.37]

24.22 [21.02, 28.36]

0.606

Heart Rate

77.00 (16.91)

73.00 (7.92)

71.25 (8.30)

0.676

Systolic Blood Pressure*

118.75 (9.19)

127.82 (10.84)

120.25 (19.33)

0.252

Diastolic Blood Pressure*

74.62 (6.25)

78.00 (8.65)

75.00 (11.22)

0.653

Oxygen Saturation (%)

97.88 (1.25)

98.73 (1.49)

99.50 (0.58)

0.134

Carbon Monoxide (ppm)

11.00 [7.75, 15.75]

1.10 [1.00, 2.50]

1.50 [1.00, 2.00]

0.004

PENN Score**

15.50 [13.50, 18.00]

15.00 [13.50, 16.00]

-

0.532

Serum Cotinine (ng/ml)

95.25 [89.95, 97.45]

68.15 [20.08, 91.78]

5.00 [5.00, 43.65]

0.09

FEV1 (% Predicted)

91.50 [89.25, 95.00]

101.00 [87.50, 106.50]

96.00 [87.50, 104.75]

0.577

FVC (% Predicted)

91.50 [86.00, 100.25]

99.00 [88.50, 111.00]

93.50 [86.25, 100.50]

0.481

FEV1/FVC Ratio

78.50 [71.75, 84.50]

81.00 [78.50, 87.00]

83.50 [80.50, 87.50]

0.573