Skip to main content
Fig. 1 | Respiratory Research

Fig. 1

From: The main e-cigarette component vegetable glycerin enhances neutrophil migration and fibrosis in endotoxin-induced lung injury via p38 MAPK activation

Fig. 1

Histological examination of VG-induced lung injury. Administration of VG, a main e-cigarette component, enhanced the histological features in mice with LPS-induced ALI. A Histological examination of H&E-stained sections revealed that the lungs of mice injected with PBS (non-treated control group), VG (VG only group), LPS (LPS only group), and VG prior to LPS (VG + LPS group) had minimal histopathological abnormalities, mild ALI, pronounced ALI, and severe ALI, respectively, demonstrating that intratracheal VG amplified lung injury pathology in mice with LPS-induced ALI. B Ashcroft lung injury scoring of Masson's trichrome-stained sections likewise showed that VG both induced lung fibrosis in mice not exposed to LPS and exacerbated lung fibrosis in mice with LPS-induced ALI. Data sets are expressed as means ± standard deviations. *p < 0.05 vs. PBS, #p < 0.05 vs. LPS; N = 6 per group

Back to article page

Respiratory Research

ISSN: 1465-993X

Contact us