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Fig. 4 | Respiratory Research

Fig. 4

From: Sputum from patients with primary ciliary dyskinesia contains high numbers of dysfunctional neutrophils and inhibits efferocytosis

Fig. 4

Expression of chemoattractant and Toll-like receptors on the surface of peripheral blood and sputum neutrophils in PCD and bronchiectasis. Peripheral blood neutrophils from patients with PCD (PCD blood, n = 5–7) and non-PCD, non-CF bronchiectasis (BE blood, n = 3–5) and purified sputum cells from patients with PCD (PCD sputum, n = 5–7) and non-PCD, non-CF bronchiectasis (BE sputum, n = 3–5) were labeled with antibodies against various neutrophil receptors. Using flow cytometry, the levels of A CXCR1, B CXCR2, C CXCR4, D C5aR, E FPR1, F TLR2, G TLR4 and H TLR6 were determined. Data are shown as A, B percentage of receptor-positive cells within the neutrophil population (defined as live CD16 + CD66b + cells) or as (C–H) median fluorescence intensities (MFI) measured in the neutrophil population (defined as live CD16 + CD66b + cells)

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Respiratory Research

ISSN: 1465-993X

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