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Fig. 3 | Respiratory Research

Fig. 3

From: CircGSAP alleviates pulmonary microvascular endothelial cells dysfunction in pulmonary hypertension via regulating miR-27a-3p/BMPR2 axis

Fig. 3

Effects of circGSAP on the proliferation, migration and mortality of PMECs. A Expression levels of circGSAP in PMECs treated with circGSAP under hypoxia (n = 3). B–D Cell proliferation, wound healing and migration analyses of PMECs overexpressing circGSAP under hypoxia (n = 5 or 4). E Cell mortality analysis of PMECs overexpressing circGSAP under hypoxia (n = 4). F Expression levels of circGSAP in PMECs after transduction with circGSAP siRNA (n = 3). G–J Cell proliferation analysis, wound healing analysis, cell migration analysis, and cell mortality analysis of PMECs with silencing circGSAP under normoxia (n = 5 or 4). All data are presented as the mean ± SEM. Scale bar 100 μm. *p < 0.05; **p < 0.01; ***p < 0.001

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Respiratory Research

ISSN: 1465-993X

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