One-minute sit-to-stand test is practical to assess and follow the muscle weakness in cystic fibrosis

Respiratory Research

Table 2 Characteristics of the patients with CF receiving IV antibiotics

Subjects, n	30
Sex (F/M)	12/18
Age, years	36 ± 14
Children (< 18 years)/Adults	5/25
F508del/F508del (yes/no)	14/16
Sweat Chloride, mmol/L	100.00 (23.40; 127.40)
Pancreatic sufficiency (yes/no)	10/20
Pseudomonas aeruginosa chronic infection (yes/no)	15/15
Diabetes (yes/no)	6/24
Smokers (yes/no)	3/27
BMI, kg/m²	20.51 (17.63; 31.09)
FEV1, L	1.98 ± 0.81
FEV1, %PV	56.79 ± 14.70
1STST, n	33 (18; 57)
1STST, %PV [26]	69.23 (40.91; 125.53)
1STST, nxkg	1976 (1035; 3477)
MVCQ, N-m	73.48 ± 31.34
MVCQ, %PV [28]	50.15 (23.86; 142.26)
CRP, mg/L (n = 29)	3 (1; 133)
IgG, g/L (n = 27)	10.50 (6.30; 25.10)
Chest X-Ray – new infiltrate (yes/no) (n = 13)	4/9
Exacerbation/Elective	11/19
Hospital/Home	16/14
Steps, n/24 h	8371.12 ± 4463.73

Data are mean ± SD if parametric or median (min; max) if non-parametric data (Kolmogorov and Shapiro–Wilk tests). N is specified when data are missing. Definition of abbreviations: n, number; F, female; M, male; yrs, years; mmol/L, millimoles per liter; BMI, body mass index; kg/m²; kilogram divided by the square meter; FEV1, forced expiratory volume in one second; L, liter; PV, predicted values; 1STST, the one-minute sit-to-stand test; nxkg, number of repetitions as a product of bodyweight expressed in kilogram; MVCQ, maximal isometric voluntary contraction of the quadriceps; N-m, Newton-meter; CRP, C-reactive protein; mg/L, milligram per liter; IgG, G-immunoglobulin; g/L, gram per liter; n/24 h number of steps per day

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