Fig. 2From: In smokers, Sonic hedgehog modulates pulmonary endothelial function through vascular endothelial growth factorEffect of SHH modulation on pulmonary artery ring relaxation. Treatment with the downstream SHH inhibitor GANT61 altered vasodilation (nā=ā27; pā<ā0.001) (a), whereas SHH upstream inhibition by cyclopamine (nā=ā27) had no effect (b). SHH activation with SAG (nā=ā27) had no effect (c)Back to article page