Table 2 Correlation between clinical parameters and HDAC2, HDAC5 and NF-κB DNA binding activity in all subjects

Age

0.04

−0.05

0.01

Pack-year

−0.28

−0.35

0.62**

BMI (kg/m²)

0.36

0.04

−0.03

FEV₁%predicted

0.53**

0.64**

−0.54**

FEV₁/FVC %

0.55**

0.68**

−0.53**

RV % predicted

−0.33

−0.33

0.59*

KCO % predicted

0.67*

0.03

−0.74*

TL_CO% predicted

0.50*

0.43

−0.81**

PaO₂

0.32

0.39

−0.54*

PaCO₂

−0.16

−0.07

0.30

MVC

0.42*

0.30

−0.50*

NF-κB

−0.59**

−0.50*

NA

HDAC 2 protein

NA

0.63**

−0.59**

HDAC5 protein

0.63**

NA

−0.50*

HDAC1 mRNA

−0.09

−0.02

0.13

HDAC2 mRNA

0.14

−0.11

−0.27

HDAC5 mRNA

−0.36

−0.44

0.12