Fig. 1
From: Cigarette smoke challenges bone marrow mesenchymal stem cell capacities in guinea pig
Schematic diagram of experimental design. Guinea pigs (starting ~ 500 g) were randomly distributed in 4 groups: Group 1; exposed and Group 2; sham-exposed to CS for subsequent BM-MSC intratracheal administration and Group 3; exposed and Group 4; sham-exposed to CS for BM-MSC vascular administration. Animals from CS groups were exposed to smoke generated by 6 non-filtered cigarettes for 4 weeks, 5 days/week using a nose-only system