Examining the role of ABC lipid transporters in pulmonary lipid homeostasis and inflammation

Respiratory Research

Table 1 Cellular expression and substrates of ABC transporters expressed in mammalian lungs

Transporter	Expressed in which lung cells	Reported substrates	References
ABCA1	Alveolar macrophages, airway smooth muscle cells, type I pneumocytes, type II pneumocytes	Cholesterol, phosphatidylcholine, phosphatidylserine, sphingolipid 1-phosphate, sphingomyelin	[28–30, 83]
ABCG1	Alveolar macrophages, airway smooth muscle cells, type II pneumocytes, T-lymphocytes, epithelial cells, dendritic cells	Cholesterol, oxysterols, phosphatidylcholine, sphingomyelin	[43, 47, 49, 84]
ABCA3	Type II pneumocytes	Cholesterol, phosphatidylcholine, phosphatidylglycerol, sphingomyelin	[15, 60, 62, 63]

ISSN: 1465-993X