Fig. 7

Interaction of p-CREB and p-Smad2/3 binding with CBP is regulated by db-cAMP. a Co-expression of p-Smads/α-SMA in fibroblasts (immunofluorescence; red: p-Smad2/3; green: α-SMA; blue: DAPI); b The expression of p-Smad2/3 in vitro (Western blot); Data are means ± SEM; n = 6 independent experiments; c p-CREB and p-Smad2/3 binding with CBP measured by co-IP, Data are means ± SEM, n = 3 independent experiments