Skip to main content

Table 1 Basic characteristics of control group and patients grouped by DanaPoint classification

From: The role of circulating thrombospondin-1 in patients with precapillary pulmonary hypertension

 

Control

All PH

PAH

LD

CTEPH

n

19

93 (100)

55 (59.1)

22 (23.7)

16 (17.2)

Male

7

37

19

15

3

Age [y]

47.2 ± 14.9

59.3 ± 15.8*

55.1 ± 16.9(*)

66.9 ± 13.0*,**

63.0 ± 9.9*,(**)

Height [cm]

169.2 ± 10.1

167.1 ± 9.8

165.6 ± 8.9

170.1 ± 11.9

168.4 ± 9.0

Weight [kg]

71.7 ± 17.3

81.0 ± 20.0(*)

81.6 ± 20.2

82.2 ± 23.7

76.8 ± 11.9

BSA [sqm]

1.81 ± 0.23

1.89 ± 0.24

1.88 ± 0.23

1.92 ± 0.30

1.87 ± 0.17

FC II-III

0

74

44

17

13

6MWD

441 ± 68.4

328 ± 142*

353 ± 110

243 ± 155*,**

347 ± 192(***)

PDEI

0

43 (46.2)

28 (51.0)

11 (50.0)

4 (25.0)

ERA

0

39 (41.9)

29 (52.7)

2 (9.1)

8 (50.0)

PC

0

14 (15.1)

12 (21.8)

0

12 (12.5)

Other

0

6 (9.5)

4 (10.8)

2 (11.8)

0

No drug

16 (83.4)

19 (20.4)

6 (10.9)

8 (36.4)

5 (31.3)

1 Drug

3 (16.6)

45 (48.4)

26 (47.3)

12 (54.5)

7 (43.7)

2 Drugs

0

25 (26.9)

19 (34.5)

2 (9.1)

4 (25.0)

≥3 Drugs

0

4 (4.3)

4 (7.3)

0

0

  1. BSA body surface area determined by DuBois formula, FC modified NYHA functional class, 6MWD 6 min walking distance. Specific drug therapy: CCB calcium channel blocker, PDEI phospho-diesterase inhibitor, ERA endothelin receptor antagonist, PC prostacyclin (inhaled/subcutaneous)
  2. *p < 0.05 vs. Control, **p < 0.05 vs. PAH, ***p < 0.05 vs. LD, marks in brackets signify statistical trends (0.05 < p < 0.01), absolute case numbers (% of cases in group)