Figure 3

Immunohistochemistry staining for IL-17A/F in human lung explants exposed to cigarette smoking medium. Human lung explants from Non-COPD and COPD subjects were cultured with 5% or 10% of CSE for 3 h or 6 h respectively. Brown color staining represents the positive signal for IL-17A/F. The arrows indicate the local immune cells in the lung tissue. Representative images from 5 Non-COPD and 4 COPD subjects are shown. Magnification: 400X.