Group | FEV1 | FVC | ||
---|---|---|---|---|
Estimated change in Δ (SE) per yr | p value | Estimated change in Δ (SE) per yr | p value | |
All | -0.68 (0.08) | <0.0001 | -0.66 (0.09) | <0.0001 |
GOLD Stage | ||||
I & II | -0.40 (0.11)1 | 0.0001 | -0.28 (0.10)1 | 0.0085 |
III | -0.86 (0.14)2 | <0.0001 | -0.89 (0.15)2 | <0.0001 |
IV | -2.08 (0.38) | <0.0001 | -2.11 (0.47) | <0.0001 |
Age, yrs | ||||
≤65 yrs | -0.61 (0.11) | <0.0001 | -0.34 (0.12)3 | 0.0058 |
>65 yrs | -0.77 (0.12) | <0.0001 | -1.04 (0.13) | <0.0001 |
Gender | ||||
Male | -0.61 (0.10) | <0.0001 | -0.64 (0.10) | <0.0001 |
Female | -0.90 (0.17) | <0.0001 | -0.74 (0.19) | <0.0001 |
Smoking status | ||||
Sustained ex-smoker | -0.91 (0.11)4 | <0.0001 | -0.88 (0.11)3 | <0.0001 |
Intermittent smoker | -0.54 (0.16) | 0.0007 | -0.55 (0.17) | 0.0014 |
Continuing smoker | 0.12 (0.25) | 0.64 | 0.14 (0.26) | 0.59 |
Inhaled steroids (baseline) | ||||
No | -0.30 (0.13)5 | 0.0273 | -0.13 (0.14)5 | 0.35 |
Yes | -0.93 (0.11) | <0.0001 | 1.01 (0.12) | <0.0001 |