From: Th2 cytokines and asthma — Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists
Gene
Polymorphism
Location
Reference
Interleukin-4 promoter
A→G
-81
[32]
C→T
-285
-590
[33]
Interleukin-4 receptor, α chain
Ile→Val
+50
[34]
Arg→Gln
+551
[35]
Ser→Pro
+503
[36]
Interleukin-13 receptor, α chain
+1398
[37]
Stat-6
G→A
+2964 (3' UTR)
[38]
BCL6
HindIII
5' untranslated region
[39]