Altered patterns of oligomerization |
   Liberation of trimeric subunits secondary to proteolytic degradation |
   Self-aggregation |
Modifications of the CRD |
   Proteolytic degradation |
   Oxidative modification |
   Local pH and calcium concentration |
Competing ligands |
   LPS |
   Microorganisms |
Host lectins with overlapping specificity |
   Mannose receptor |
   Other collectins (SP-A, mannose-binding lectin) |
   Non C-type lectins (such as ficolins) |