Supplementary Table 2 Chromosomal regions showing evidence for linkage to asthma and related phenotypes

5q23-33

Total IgE

Dutch, Amish, Caucasian (UK)

[S8,S9,S10]

Total IgE, specific IgE, eosinophil count

Australian

[S11]

Specific IgE

African American

[S12]^*

Atopic dermatitis

Caucasian (UK), German/Swedish

[S13,S14]

Asthma/atopy

Japanese

[S6,S15]^*

Eosinophil count

Caucasian (US)

[S16]

Hypereosinophilia

Caucasian (US)

[S17]

Bronchial hyperresponsiveness

Dutch, Hutterites

[S3,S18]^*

6p21-23

Specific IgE

Caucasian (US)

[S1,S19]

Asthma, IgE

German/Swedish

[S5]^*

Allergic asthma

Colombian

[S20]

Eosinophil count

Caucasian (Australian)

[S2]^*

11q13

IgE

Caucasian (UK)

[S21,S22]

IgE, positive skin test

Caucasian (Australian)

[S2]^*

Specific IgE

Caucasian (Australian), African American

[S11,S12]

Bronchial hyperresponsiveness, log IgE

Caucasian (UK)

[S10]

Bronchial hyperresponsiveness

Caucasian

[S23]

Atopy

Japanese

[S24]

Asthma, atopy

Caucasian

[S25]

Atopic dermatitis

German

[S26]

12q14-24

Asthma

German/Swedish Caucasian (US)

[38,S27]^*

Caucasian (UK)

[S28]

Asthma, atopy

Afro-Caribbean

[S29]

Total IgE, asthma

Afro-Caribbean, Amish

[S30]

Total IgE

German

[S31]

Bronchial hyperresponsiveness

Hutterites

[S3]^*

Eosinophil count

French

[S7]^*

13q11-32

Atopic dermatitis

German/Swedish

[S14]

Specific IgE

Caucasian (UK)

[S1]^*

Atopy

Caucasian (Australian)

[S2]^*

Eosinophil count

French

[S7]^*

Asthma

Caucasian (US), Japanese

[38^*,S6^*]

Atopic asthma

Japanese

[S32]