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Table 1 Chemokine receptors and their ligands

From: Chemokines and their role in airway hyper-reactivity

CXC chemokine receptors

CC chemokine receptors

CXCR1: IL-8, GCP-2

CCR1: MIP-1α, RANTES, MCP-3, MIP-δ

CXCR2: IL-8, GCP-2, GROα,β,γ, ENA-78

CCR2: MCP-1 to MCP-5

CXCR3: IP-10, MIG, ITAC

CCR3: Eotaxin, MCP-3,4, RANTES

CXCR4: SDF-1

CCR4: TARC, MDC

CXCR5: BCA

CCR5: MIP-1α, RANTES, MIP-1β

 

CCR6: LARC, MIP-3α

 

CCR7: SLC, MIP-3β

 

CCR8: I-309, TARC, MIP-1β

 

CCR9: MIP-1α,β, MCP-1, MCP-5

 

CCR10: SLC, LARC, BLC-1, ESkine

 

CCR11: MCP-1 to MCP-5, eotaxin

  1. GCP-2, granulocyte chemotactic protein-2; GRO, growth-related oncogene; IP-10, γ -interferon-inducible protein 10; MIG, monokine-induced by γ -interferon; TARC = T cell and activation-related chemokine; SLC = secondary lymphoid tissue chemokine; SDF-1, stromal cell-derived factor; BCA, B-cell chemoattractant; ENA, epithelial cell-derived neutrophil-activating factor; RANTES, regulated upon activation normal T cell expressed and secreted; ITAC, interferon-inducible T cell α chemoattractant.