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Figure 6 | Respiratory Research

Figure 6

From: Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis

Figure 6

Cathepsin K transgenic mice exhibit decreased lung resistance upon bleomycin challenge. Cathepsin K transgenic mice (black bars) and wild-type mice (white bars) were treated with bleomycin for 14 days. Subsequently, mice were anaesthesized and their lung resistance (A) and dynamic compliance (B) were assessed and compared to controls (A, B). The data are shown as mean ± SD of at least n = 10 mice per group and time point. * indicates significant increase (p < 0.05) compared to cathepsin K transgenic mice. + indicates significant decrease (p < 0.05) compared to the respective mock-treated mice.

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Respiratory Research

ISSN: 1465-993X

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