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Table 3 Ratio of mean endpoint to baseline levels for cysteinyl leukotrienes and histamine

From: Salmeterol plus fluticasone propionate versus fluticasone propionate plus montelukast: a randomised controlled trial investigating the effects on airway inflammation in asthma

Marker

SFC (n = 33)

FP/M (n = 33)

Treatment ratio (95% CI)

Ā 

Baseline

Ratio* (95% CI)

Baseline

Ratio* (95% CI)

Ā 

C-LT (ng/ml)

1.14

0.97 (0.68, 1.37)

0.91

0.54ā€  (0.38, 0.77)

1.80 (1.09, 2.94)ā€”

Histamine (ng/ml)

5.10

0.65 (0.36, 1.18)

5.16

0.95 (0.52, 1.73)

0.69 (0.30, 1.62)

  1. * ratio of endpoint value to baseline value, adjusted for baseline values; ā€  within-group ratio p = 0.005; ā€” between group p = 0.021
  2. CI, confidence interval; FP/M, fluticasone propionate plus montelukast; n, number; SFC, salmeterol plus fluticasone propionate