Table 3 β2-agonist or placebo regular inhalation and bronchoscopy protocol. Samples (lavage and brush biopsies) from five bronchoscopic procedures were obtained from the unchallenged and Ag challenged lung segments according to the procedure day indicated. Seven asthmatics enrolled in the drug arm, and 4 of these same subjects re-enrolled in the placebo arm. A baseline sample and a 24 hr post Ag challenge sample were obtained before (days 1 and 2) and after (days 18 and 19) a two week period of regular albuterol or placebo use. The initial baseline unchallenged and challenged lung segments were resampled following one additional week of regular albuterol or placebo use which were discontinued 12 hr before the final bronchoscopic procedure on day 25.