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Figure 4 | Respiratory Research

Figure 4

From: Alterations in vasodilator-stimulated phosphoprotein (VASP) phosphorylation: associations with asthmatic phenotype, airway inflammation and β2-agonist use

Figure 4

Numbers of epithelial cells in control segment BAL fluid from asthmatics before and after regular β-agonist or placebo inhalation. Epithelial cell numbers in unchallenged lung segment BAL fluid prior to any inhalation (A, day 1) and in unchallenged lung segment BAL fluid after two weeks regular inhalation of albuterol or placebo (B, day 18). The numbers of cells stained with Alcian Blue for mucous (gray shaded bars), nonspecific esterase for ciliated (hatched bars), other columnar cells (open bars) and the total of these three (solid bars) per ml were increased after two weeks of regularly inhaled albuterol compared to placebo (p < 0.001 for both Alcian blue and total groups). There was also a significant effect for day in Alcian blue stained cells (day 1 versus day 18, p = 0.014) and a significant group × day interaction in Alcian blue and total cell groups for albuterol inhalation (p = 0.004 and p = 0.014, respectively).

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Respiratory Research

ISSN: 1465-993X

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