Figure 7From: TGF-β1 increases proliferation of airway smooth muscle cells by phosphorylation of map kinasesRole of EGF, FGF-2, PDGF and IGF-I in TGF-β1 induced proliferation of ASMCs. Confluent and growth-arrested ASMCs were treated with TGF-β1 (1 ng/ml) in the absence or presence of neutralizing antibodies to EGF, FGF-2, PDGF and IGF-I for 48 hours prior to [3H]-thymidine incorporation assay. # p < 0.01, compared to untreated control (C). There were no significant differences (p > 0.05) in the DNA synthesis between TGF-β1 treated cells with and without pretreatment with these antibodies.Back to article page