Table 1 Patient Demography
Characteristic | Study A | Study B |
|---|---|---|
Number of subjects screened | 33 | 206 |
Number of subjects randomised | 33 | 75* |
Mean age (years) (sd) | 40.2 (14.3) | 36.4 (12.5) |
Sex: Males/females % | 48/52 | 48/52 |
Mean % predicted FEV1 (sd) | 80.5 (12.4) | 82.8 (17.0) |
Mean % reversibility (sd) | 18.9 (6.9) | 28.7 (17.6) |
Duration of asthma (n): | ||
< 5 years | 2 | 5 |
10–20 years | 9 | 31 |
>20 years | 22 | 39 |
Current smoker, n (%) | 1 (3%) | 12 (16%) |
Dose of ICS at screening for randomised patients (n) | ||
BDP: 200 mcg bd/400 mcg bd/500 mcg bd | 2/1/0 | 5/23/15 |
Budesonide: 200 mcg bd/300 mcg bd/400 mcg bd/600 mcg bd | 10/1/13/0 | 0/0/21/1 |
FP: 100 mcg/250 mcg bd | 2/4 | 2/8 |