Figure 6
From: Cysteinyl-leukotrienes in the regulation of β2-adrenoceptor function: an in vitro model of asthma
Effect of the pretreatment with the PKC inhibitor GF109203X on salbutamol-induced relaxation in challenged human bronchial rings. Relaxant responses to salbutamol in five carbachol-contracted human bronchial rings. Values of 100 and 0 on y-axis represent maximal force in response to 10-6M carbachol and minimal force at 10-4M salbutamol, respectively. ■, challenged-untreated rings; ○, rings pre-treated with 10-7M GF109203X; ▲, ring pre-treated with 10-6M GF109203X.