Figure 2

After eosinophilia had been established in the immunized mice anti-Fas mAb or isotype control Ab was administered locally to the lungs followed by BAL and tissue sampling at 8 and 24 hours. The number of eosinophils in airway lumen (A) and airway tissue (B) was quantified as described in detail in the methods section. White bars represent mice given control Ab and black bars mice given anti-Fas mAb. Error bars indicate the standard error of the mean for each group of mice (n = 8, ** = p < 0.01). Peribronchial eosinophilia induced by the OVA challenges is shown in (C).