Figure 4
Mean linear intercepts, lung desmosine and elastase burden in various strains of mice following bleomycin challenge. (A) Mean linear intercepts (Lm) in Balb/C, C57 Bl/6 and pallid mice after bleomycin challenge. Data are from 10 animals for each time point and are given as mean ± SD. *: p < 0.01 versus respective saline-treated group. (B) Lung desmosine content in Balb/C, C57 Bl/6 and pallid mice after bleomycin treatment. Data from 10 animals for each time point are given as mean ± SD and represent per cent change over respective saline-treated controls (Balb/C: 2.50 ± 0.28 μg/lung; C57 BI/6: 2.48 ± 0.30 μg/lung; pallid: 2.44 ± 0.32 μg/lung). *: p < 0.01 versus respective saline-treated group. (C) Lung elastase burden in Balb/C, C57 Bl/6 and pallid mice at 7 days after bleomycin treatment. Data are given as mean ± SD of the number of gold particles per μm2. *: p < 0.01 versus respective saline-treated group.