Figure 1

Emphysema and fibrosis after bleomycin challenge. The volume densities of emphysematous changes (Vv(e)) (A) and fibrosis (Vv(f)) (B) were quantitated by morphometry (point counting) on hematoxylin/eosin or Masson's trichrome stained lung sections, at various times after bleomycin. Data from 10 animals for each time point are given as mean ± SEM of per cent lung volume densities. *: p < 0.01 versus respective untreated controls (0 days).