| | | BAPTA-AM | SN50 | SN50M | parthenolide |
---|
C. pneumoniae | - | + | + | + | + | + |
TNF-α (3 h) | 22.2* ± 7.5 | 703.4 ± 91 | 155.5* ± 30.7 | 122.6* ± 41 | 705.8 ± 65 | 125* ± 15.2 |
MIP-2 (6 h) | 211* ± 28 | 4516 ± 182 | 2725* ± 413 | 2436* ± 253 | 3648 ± 49 | 1602* ± 24 |
- Mean values are given in pg/ml ± SD of four independent experiments. Asterisk indicates a significant difference (P < 0.0001) compared to C. pneumoniae infected type II cells (column 2) or C. pneumoniae infected type II in the presence of SN50M (column 5).