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Table 4 Lymphocyte subpopulations in bronchoalveolar lavage from normal subjects and patients with SARS

From: Persistence of lung inflammation and lung cytokines with high-resolution CT abnormalities during recovery from SARS

 

Normal subjects

SARS patients

  

60 days

90 days

 

(n = 9)

(n = 12)

(n = 6)

Lymphocytes (103 cells/ml)

5.8 ± 1.4

39.2 ± 12.1*

9.7 ± 2.4†

CD3 cells (%)

39.7 ± 6.4

33.1 ± 6.7

37.8 ± 6.1

CD3 cells (103 cells/ml)

2.4 ± 0.5

16.3 ± 6.4*

3.3 ± 0.7

CD4 cells (%)

9.2 ± 2.6

8.7 ± 2.2

10.4 ± 4.3

CD4 cells (103 cells/ml)

1.2 ± 0.3

4.4 ± 2.0*

0.8 ± 0.3

CD8 cells (%)

6.6 ± 2.6

20.1 ± 5.5*

13.2 ± 3.3

CD8 cells (103 cells/ml)

0.7 ± 0.1

11.8 ± 4.7*

1.1 ± 0.2†

CD4/CD8 (ratio)

1.89 ± 0.22

0.62 ± 0.12*

0.73 ± 0.12†

B cells (%)

6.7 ± 1.2

3.2 ± 0.8

2.8 ± 0.6

B cells (103 cells/ml)

0.4 ± 0.1

1.4 ± 0.7

0.3 ± 0.1

NK cells (%)

1.8 ± 0.2

8.8 ± 2.6*

5.8 ± 2.1

NK cells (103 cells/ml)

0.1 ± 0.03

4.0 ± 2.4**

0.3 ± 0.1†

  1. Abbreviation: HRCT, high resolution computed tomography; NK, natural killer.
  2. *p < 0.05, ** p < 0.01 compared with normal subjects.
  3. †p < 0.05 compared with SARS patients at 60 days.
  4. Data are mean ± SEM.
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Respiratory Research

ISSN: 1465-993X

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