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Table 4 Impact of hyperoxia over 48 h on invasively and noninvasively measured respiratory parameters

From: Invasive versus noninvasive measurement of allergic and cholinergic airway responsiveness in mice

Noninvasive measurement

 

Invasive measurement

 

EF50

TE

VT

f

 

RL

Cdyn

GL

EF50

TE

VT*

f

Control

2.36 ± 0.12

0.13 ± 0.01

0.20 ± 0.01

251 ± 14

 

1.44 ± 0.27

0.017 ± 0.004

0.72 ± 0.15

1.01 ± 0.13

0.3 ± 0.03

0.11 ± 0.02

106 ± 9

Hyperoxia

2.30 ± 0.41

0.14 ± 0.02

0.20 ± 0.02

245 ± 41

 

1.27 ± 0.29

0.018 ± 0.007

0.85 ± 0.18

0.93 ± 0.15

0.32 ± 0.04

0.14 ± 0.02

99 ± 15

  1. Values are means ± SD from 8 C57BL/6 mice per group. *P < 0.05 vs. control mice. VT: tidal volume, EF50: tidal midexpiratory flow, TE: time of expiration, f: respiratory rate, RL: pulmonary resistance, Cdyn: dynamic compliance, GL: pulmonary conductance (GL = 1/RL).