Table 1 Baseline patient characteristics

Gender (M/F)*

687 / 141

Age (y)

67 (9)

Pack-years

56 (28)

Active smoking*

29%

BMI (kg/m ² )

28.1 (5.5)

FEV ₁ L

1.65 (0.65)

FEV ₁ %

56 (28)

PaO ₂ (mmHg)

67.4 (9.6)

FVC L

3.130 (0.94)

FVC%

88 (19)

FEV1/FVC

53 (11)

6MWD (m)

438 (104)

Dyspnea (mMRC)†

1 (0-4)

BODE index†

4 (0-6)

IC/TLC

0.35 (0.10)

K _CO

74 (24)

Charlson index†

1 (0-5)

Exacerbations ≥2 per patient-years ^‡

0.15 (0.01)

Hospitalization ≥1 per patient-years ^‡

0.12 (0.01)

Inhaled anticholinergic*

75%

Inhaled β2-agonist*

74%

Inhaled corticosteroid*

65%

CAT†

11 (2-27)

CCQ†

1,3 (0-3.7)