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Table 1 COPDGene study subjects

From: Paired inspiratory-expiratory chest CT scans to assess for small airways disease in COPD

 

All subjects

Severe emphysema‡

No emphysema§

N

8517

1188

5769

Age

59.6 (9.0)

65.5 (7.7)

57.6 (8.6)

Sex

Male

4535 (53.2%)

711 (59.8%)

2849 (49.4%)

Female

3982 (46.8%)

477 (40.2%)

2920 (50.6%)

Race

African American

2668 (31.3%)

190 (16.0%)

2156 (37.4%)

White

5849 (68.7%)

998 (84.0%)

3613 (62.6%)

Current smoking

4463 (52.4%)

259 (21.8%)

3547 (61.5%)

Pack-years of smoking

44.3 (24.8)

55.4 (27.8)

40.8 (22.6)

GOLD Stage

[54 missing]†

[3 missing]†

[40 missing]†

0

3674 (43.4%)

17 (1.4%)

3241 (56.6%)

1

668 (7.9%)

47 (4.0%)

414 (7.2%)

2

1636 (19.3%)

263 (22.2%)

870 (15.2%)

3

965 (11.4%)

458 (38.7%)

217 (3.8%)

4

502 (5.9%)

396 (33.4%)

33 (0.6%)

Unclassified*

1018 (12.0%)

4 (0.3%)

954 (16.7%)

  1. Non-smokers were excluded. Mean (SD) or N (%) is shown.
  2. *Unclassified: FEV1 < 80% predicted with FEV1/FVC > 0.7.
  3. †GOLD Stage is missing in subjects whose spirometry failed quality control.
  4. ‡Severe emphysema defined by Insp-950HU > 15% ex-smokers, > 14% current smokers.
  5. §No emphysema defined by Insp-950HU < 5% ex-smokers, < 4% current smokers.