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Table 1 Biometry and volumetry data

From: Ex vivo expanded human cord blood-derived hematopoietic progenitor cells induce lung growth and alveolarization in injured newborn lungs

 

PBS (8)

CD34+ Fresh (3)

CD34+ Basic (12)

CD34+ Dex (8)

Body wt (g)

26.37 ± 2.76

21.00 ± 2.95*

25.50 ± 4.43

23.01 ± 3.29*

V(lu) (μl)

669 ± 161

595 ± 105

814 ± 153*

738 ± 113

A A (ae/lu)

21.3 ± 4.7

20.2 ± 3.0

21.1 ± 3.1

24.0 ± 4.9

V(ae) (μl)

136 ± 23

118 ± 12

170 ± 31*

177 ± 43*

V(ae)/BW (μl/g)

5.33 ± 0.48

5.69 ± 0.82

6.84 ± 1.35**

7.45 ± 1.92**

  1. Animals were treated with freshly isolated CB-CD34+ cells (0.5 x 106 cells/pup) or CB-CD34+ cells expanded in basic medium or DEX medium (1-2 x 106 cells/pup). Sham controls received equal volume PBS.
  2. Values represent mean ± SD of (n) animals per group.
  3. V(lu): lung volume; AA(ae/lu): areal fraction of air-exchanging parenchyma; V(ae): volume of air-exchanging parenchyma.
  4. *: P < 0.05; **: P < 0.01 versus PBS-treated sham controls.
  5. (Student-t test).