Figure 7
Analysis of alveolarization. Top. Morphometric analysis of mean cord length (MCL). Values represent mean ± SD of at least 3 animals per group. *: P < 0.01 versus PBS-treated sham controls (ANOVA with post hoc Scheffe test). Bottom. Representative micrographs showing lung parenchyma of animals treated with PBS (sham, A), fresh CB-CD34+ cells (B), CB-CD34+ cells expanded in basic medium (C) or CB-CD34+ cells expanded in DEX medium (D), 8 weeks post inoculation. Animals treated with DEX-expanded CD34+ cells (D) showed more advanced alveolar architectural remodeling with more complex alveolar septation than animals of the other study groups (A-C). Hematoxylin-eosin staining, original magnification: X200.