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Figure 6 | Respiratory Research

Figure 6

From: Ex vivo expanded human cord blood-derived hematopoietic progenitor cells induce lung growth and alveolarization in injured newborn lungs

Figure 6

Analysis of leukocyte differentiation of CB-CD34+ cells. Immunohistochemical analysis of leukocyte differentiation using a human-specific anti-CD45 (leukocyte common antigen) antibody. A. Representative micrograph of lungs of animal treated with DEX-expanded CB-CD34+ cells at post-inoculation week 8. Scattered CD45-positive mononuclear cells are noted along the alveolar wall. CD45-immunoreactivity is absent in murine thymic lymphocytes (negative control) (B) and diffusely positive in human lymphocytes (C, human tonsil, positive control), confirming the human-specific nature of the antibody. A-C: avidin-biotin peroxidase staining, hematoxylin counterstain. Original magnification: X400.

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