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Table 2 Identification of polymorphisms in MMP-1 cigarette smoke-responsive element

From: Functional characterization of the matrix metalloproteinase-1 cigarette smoke-responsive region and association with the lung health study

SNP*

SNP ID

WW†

WM†

MM†

NC‡

Not amplified for this SNP

Total N

Failed %

W%

M%

17 T/A

rs484915

167

265

126

4

20

582

4.1

53.7

46.3

352 G/A

rs470307

554

9

0

0

19

582

3.3

99.2

0.8

412 T/A

NA

571

5

0

0

6

582

1.0

99.6

0.4

712 G/A

rs2408490§

368

149

16

4

45

582

8.4

83.0

17.0

724 T/A

rs12279710

534

3

0

1

44

582

7.7

99.7

0.3

759 T/G

rs7107224

391

162

19

5

5

582

1.7

82.5

17.5

816A/C

rs1155764§

383

157

21

19

2

582

3.6

82.3

17.7

1164C/T

rs34695796

537

19

1

9

16

582

4.3

98.1

1.9

1227 G/A

NA

558

6

0

2

16

582

3.1

99.5

0.5

1283 G/A

NA

554

5

0

7

16

582

4.0

99.6

0.4

1284 G/A

NA

499

49

3

15

16

582

5.3

95.0

5.0

  1. * Position in AF023338.
  2. † “W” denotes wild-type allele; “M” denotes mutant allele.
  3. ‡Results are not consistent between forward primer sequencing and reverse primer sequencing.
  4. §Rs2408490 and rs1155764 are in complete LD with r2 = 1 in Hapmap database.