Table 5 Comparison of pulmonary function tests (PFTs) obtained at most recent follow-up between clinically diagnosed FPF (FPF-DC), FPF diagnosed through screening (FPF-DS) and sporadic groups
PFT parameter | Number (%) of FPF-DC patients with abnormal findinga | Mean % of predicted value +/− SD | Number (%) of FPF-DS patients with abnormal findinga | Mean % of predicted value +/− SD | Number (%) of sporadic PF patients with abnormal findinga | Mean % of predicted value +/− SD |
|---|---|---|---|---|---|---|
FVC | 32/44 (72.7 %) | 70.5 % +/−19.5 % | 6/16 (37.5 %) | 90.3 % +/−17.8 % | 33/47 (70.2 %) | 69.9 % +/− 18.6 % |
TLC | 20/29 (69.0 %) | 69.9 % +/− 17.0 % | 5/15 (33.3 %) | 85.6 % +/−20.3 % | 20/32 (62.5 %) | 69.2 % +/− 17.2 % |
FEV1 | 35/43 (81.3 %) | 68.6 % +/− 18.6 % | 7/16 (43.8 %) | 83.2 % +/−15.6 % | 32/47 (68.0 %) | 71.8 % +/− 18.5 % |
DLCO | 34/35 (97.1 %) | 47.6 % +/− 20.1 % | 15/16 (93.8 %) | 60.2 % +/−13.8 % | 35/38 (92.1 %) | 47.3 % +/− 26.4 % |
Isolated reduction in DLCO (other PFTs normal) | 4/25 (16.0 %) | N/C | 6/15 (40.0 %) | N/C | 2/29 (6.9 %) | N/C |