PFT parameter | Number (%) of FPF-DC patients with abnormal findinga | Mean % of predicted value +/− SD | Number (%) of FPF-DS patients with abnormal findinga | Mean % of predicted value +/− SD | Number (%) of sporadic PF patients with abnormal findinga | Mean % of predicted value +/− SD |
---|---|---|---|---|---|---|
FVC | 23/45 (51.1 %) | 78.4 % +/− 15.4 % | 6/16 (37.5 %) | 92.7 % +/−16.8 % | 24/46 (52.2 %) | 80.1 % +/− 19.3 % |
TLC | 20/41 (48.7 %) | 78.5 % +/− 15.4 % | 6/16 (37.5 %) | 86.6 +/−19.6 % | 19/41 (46.3 %) | 80.2 % +/− 17.9 % |
FEV1 | 22/42 (52.3 %) | 79.1 % +/− 15.1 % | 5/16 (31.2 %) | 87.1 % +/−12.9 | 21/46 (45.6 %) | 81.5 % +/− 17.6 % |
DLCO | 39/40 (97.5 %) | 56.4 % +/− 15.7 % | 12/16 (75.0 %) | 66.4 % +/−18.4 | 37/42 (88.0 %) | 57.2 % +/− 23.2 % |
Isolated reduction in DLCO (other PFTs normal) | 12/36 (33.3 %) | N/C | 6/16 (37.5 %) | N/C | 14/39 (35.9 %) | N/C |