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Table 3 Mean ratios (between AZD8848 and placebo) for levels of α 2 -macroglobulin and tryptase, respectively, in nasal lavages obtained 24 hours after the last allergen challenge in the repeat challenge/treatment study

From: Repeated intranasal TLR7 stimulation reduces allergen responsiveness in allergic rhinitis

Variable

Mean ratio

95% CI

P-value

α2-Macroglobulin

0.50

0.25-0.97

0.020

Tryptase

0.62

0.35-1.10

0.049

  1. α2-Macroglobulin was reduced in patients who had received AZD8848 (p < 0.05, c.f. placebo). Similarly, lower levels of tryptase were observed in this group (p < 0.05, c.f. placebo).
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Respiratory Research

ISSN: 1465-993X

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