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Figure 1 | Respiratory Research

Figure 1

From: The ion channel transient receptor potential melastatin-2 does not play a role in inflammatory mouse models of chronic obstructive pulmonary diseases

Figure 1

TRPM2 deficiency has no effect on the ozone-induced BAL inflammation. TRPM2-deficient mice (grey bars) or their wild type counterpart (white bars) were exposed to ozone (3 ppm for 4 hours, hatched bars) or air (plain bars) as described in methods section. Animals were killed for bronchoalveolar lavage differential cell counts and soluble mediator measurement at 3 and 24 hours after the end of exposure. Data are shown as mean ± SEM of 2 different experiments, each including 10-11 animals per group. Significance (P < 0.05), indicated by *, is against the air-exposed mice for each strain. No statistical significance was observed between deficient and wild type animals on all the parameters measured.

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Respiratory Research

ISSN: 1465-993X

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