From: Epidemiology, radiology, and genetics of nicotine dependence in COPD
Variables | Control (n = 507) | COPD (n = 335) | p |
---|---|---|---|
Age, years | 53.8 ± 6.9 | 59.2 ± 7.8 | <.0001 |
Male, n (%) | 276(54.4) | 185(55.2) | 0.82 |
White, n (%) | 245(48.3) | 244(72.8) | <.0001 |
BMI, kg/m2 | 28.5 ± 5.9 | 27.1 ± 5.8 | 0.001 |
FTND score | 4.6 ± 2.5 | 4.7 ± 2.4 | 0.49 |
Nicotine dependence (FTND ≥6), n (%) | 196(38.7) | 133(39.7) | 0.76 |
Smoking amount, pack-years | 37.2 ± 19.2 | 51.7 ± 28.8 | <.0001 |
Average number of cigarette smoked per day | 20.2 ± 8.9 | 23.8 ± 10.8 | <.0001 |
Cigarettes/day, current | 16.9 ± 9.8 | 17.3 ± 10.8 | 0.56 |
Smoking starting age, years | 17.0 ± 5.3 | 16.4 ± 4.8 | 0.09 |
FEV1/FVC, ratio | 0.79 ± 0.05 | 0.53 ± 0.12 | <.0001 |
FEV1, % of predicted | 97.6 ± 12.3 | 55.2 ± 16.4 | <.0001 |
% Emphysema at -950 HU‡, % | 1.84 ± 2.21 | 8.81 ± 9.75 | <.0001 |
% Gas trapping, % | 10.5 ± 9.9 | 32.9 ± 19.3 | <.0001 |
Pi10 | 3.75 ± 0.12 | 3.81 ± 0.12 | <.0001 |