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Table 2 Sleep and metabolic parameters before and after CPAP use

From: Weight and metabolic effects of cpap in obstructive sleep apnea patients with obesity

 

Baseline

Post-CPAP

p value

CPAP pressure (cm H2O)

 

10 ± 3.2

 

CPAP use (days)

 

165 ± 17

 

CPAP use (Hrs/day)

 

5.3 ± 0.35

 

ESS

14.6 ± 1

9.5 ± 1

0.002

Lowest O2 sat. (%)

77 ± 3

89.3 ± 3

0.005

Mean O2 sat. (%)

93.2 ± 0.7

93.8 ± 0.62

0.5

Systolic blood pressure (mmHg)

124 ± 3

129 ± 4

0.07

Diastolic blood pressure (mmHg)

76 ± 2

76 ± 2

0.99

Heart rate (bpm)

77 ± 3

72 ± 3

0.27

Body weight (Kg)

108 ± 5.3

109.6 ± 5.4

0.04

BMI (Kg/m2)

36.5 ± 1.8

37.1 ± 1.8

0.06

Leptin (ng/dL)

22.7 ± 6

21.6 ± 4

0.61

Adiponectin (ng/mL)

8.3 ± 1.2

8.2 ± 1.2

0.94

Resistin (ng/mL)

3.1 ± 0.4

3.2 ± 0.4

0.79

HOMA-IR

5.9 ± 1

7.5 ± 1.2

0.04

ISI

2.6 ± 0.55

2.1 ± 0.33

0.09

QUICKI

0.31 ± 0.008

0.3 ± 0.006

0.02

  1. Significant differences compared to baseline (p ≤ 0.05) appear in bold. ESS: Epworth Sleepiness Scale, QUICKI: quantitative insulin sensitivity check index, ISI: Insulin sensitivity index, HOMA-IR: homeostasis model assessment.