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Table 1 Characteristics of the study population based on KORA F4, persons aged 40-65 years with blood pressure measurements and lung function tests

From: High blood pressure, antihypertensive medication and lung function in a general adult population

 

Men (N = 618)

Women (N = 701)

 
 

Mean ± SD

Mean ± SD

P-Value#

Age (years)

51.6 ± 5.8

51.5 ± 5.6

0.83

BMI (kg/m2)

28.0 ± 4.5

26.9 ± 5.2

<0.01

Packyears (y)

21.8 ± 20.1

13.4 ± 12.9

<0.01

Blood pressure

   

   Mean SBP (mm Hg)

126.3 ± 16.1

114.9 ± 15.8

<0.01

   Mean DBP (mm Hg)

80.1 ± 9.8

74.1 ± 9.0

<0.01

Lung function

   

   FEV1 (l)

3.9 ± 0.7

2.8 ± 0.5

<0.01

   FVC (l)

5.0 ± 0.8

3.6 ± 0.6

<0.01

   FEV1 % predicted$

107.2 ± 16.2

110.1 ± 17.2

<0.01

   FVC % predicted$

111.5 ± 13.7

120.2 ± 16.0

<0.01

 

n (%)

n (%)

P-Value #

Pulmonary and cardiac diseases

   

   Asthma

50 (8.1)

69 (9.8)

0.27

   Chronic bronchitis

49 (8.0)

58 (8.3)

0.81

   Heart attack

17 (2.8)

11 (1.6)

0.14

   Stroke

15 (2.4)

2 (0.3)

<0.01

Smoking status

   

   current

155 (25.1)

150 (21.4)

0.11

   former

268 (43.4)

236 (33.7)

<0.01

   never

195 (31.6)

315 (45.0)

<0.01

High blood pressure and medication*classes

   

   HBP

143 (23.1)

72 (10.3)

<0.01

   HBP or medication*

221 (35.8)

177 (25.3)

<0.01

   HBP and medication*

46 (7.4)

22 (3.1)

<0.01

   Only HBP

97 (15.7)

50 (7.1)

<0.01

   Only medication*for HBP

78 (12.6)

105 (15.0)

0.22

Medication* for HBP

124 (20.1)

127 (18.1)

0.37

   Beta-blocker

68 (11.4)

82 (11.8)

0.67

   ACE inhibitor

52 (8.4)

44 (6.3)

0.14

   Angiotensin antagonists

41 (6.6)

33 (4.7)

0.13

   Diuretics

63 (10.2)

60 (8.6)

0.32

   Calcium antagonists

25 (4.1)

25 (3.6)

0.65

   Other antihypertensive drugs

3 (0.5)

4 (0.6)

0.83

  1. SBP: systolic blood pressure; DBP: diastolic blood pressure; HBP: high blood pressure
  2. (≥140/90 mmHg); FEV1: forced expiratory volume in one second; FVC: forced vital capacity;
  3. * Medication: antihypertensive medication; $ % predicted values according to Quanjer; # Obtained from the chi-square test when comparing frequencies and from the Kruskal Wallis test when comparing mean values.