Figure 3
From: Attenuation of antigen-induced airway hyperresponsiveness and inflammation in CXCR3 knockout mice
Effect of CXCR3 deficiency on airway responsiveness to inhaled methacholine. Immunized and challenged WT mice showed significantly higher airway responsiveness at 25 mg/ml mechacholine than all other groups as determined by one-way ANOVA, n = 8-12 animals per group. Note that airway responsiveness was significantly higher in immunized and challenged WT mice compared with the similarly-treated CXCR3 KO mice as determined by unpaired t-test (p < 0.05).