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Figure 3 | Respiratory Research

Figure 3

From: Hypoxia-inducible factor-1 α/platelet derived growth factor axis in HIV-associated pulmonary vascular remodeling

Figure 3

Presence of medial wall thickness in the pulmonary arteries of HIV-Tg rats. Immuno-histochemistry of paraffin embedded lung sections with anti- α smooth muscle actin (brown) (a-b) and factor VIII (brown) (c-d) indicated abnormal vascular lesions with significant medial wall thickening in the lung sections from HIV-Tg rats (b, d) compared with WT-controls (a, c). Representative images were captured at 10× original magnification (scale bar: 100 μm).

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Respiratory Research

ISSN: 1465-993X

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