Figure 1

CAT2 induction by allergen challenge. In (A), wild type and STAT6-deficient mice were allergen challenged with OVA or saline (Sal) and CAT2 expression was determined by Northern blot analysis. In (B), the expression ofCAT2 following intranasal challenges with Asp or saline is shown. In (C), CAT2 expression in wild type and IL-4 lung transgenic mice was determined by Northern blot hybridization. The 4.5 kb band of CAT2 mRNA is shown. The Ethidium bromide (EtBr)-stained gel is also shown. Each lane represents whole lung RNA from an individual mouse.