Figure 6
Effect of the NK 1 receptor antagonist on cigarette smoke-induced inflammation in bronchoalveolar lavage fluid. Total bronchoalveolar lavage (BAL) cells and cell differentiation in BAL fluid of C57BL/6 mice upon IP injection with either 0.1 or 1 μg/μl of the NK1 receptor antagonist RP 67580 or diluent and subsequent exposure to air or cigarette smoke for 2 weeks: (A) Total BAL cells, (B) macrophages, (C) dendritic cells, (D) neutrophils and (E) lymphocytes. Results are expressed as means ± SEM. N = 8 animals per group (* p < 0.05).